“One moment they are happy, and the next moment, they start crying!” This is the first thing that you will notice in people suffering from PTSD commonly known as Post Traumatic Stress Disorder.

The name suggests the group of people who lived through trauma or horror. If a person exposes himself to some horrific events or trauma, the person has PTSD. And those who think that it may pass with time did not understand the real issue.

The fact is that it becomes more severe with time i.e., the more you ignore the symptom, the more you shall feel depressed. The negative thoughts will cover your mind and actively respond to trauma-related stimuli.

Let’s try to discuss some real case studies that shall help you understand this disorder clearly. It will clear your doubts & give you enough insight into what you can do if you have a patient with PTSD at home.

Case Reports with the patients suffering from PTSD:

Introduction of Paroxetine Monotherapy:

This study is all about checking the efficiency of two drugs combined and given to patients diagnosed with PTSD. Participants ranged in age from 18-60 with moderate to severe symptoms. The dose is administered for two weeks.

The team conducting the case study also added mirtazapine for the cases that failed to show any improvement even after administering the dosage for two weeks. After completion of this study, the medical professionals issued a statement. It stated that at the end of eight weeks of follow-up, the patients showed improvement with paroxetine monotherapy. For further reference please check the detailed study.

Introduction of Benzodiazepine for Veterans Health Administration:

This study tracks the changes you see in PTSD patients prescribed Benzodiazepine. Our primary focus includes incidence rates, discontinuation rates, and temporal shifts.

The medical professionals chose the national VHA (Veterans Health Administration) database because of Benzodiazepine in their prescription.

As a result of the closure, the experts concluded that this drug prevalence in PTSD veterans declined from 31.3% to 10.7% from 2009 to 2019.

The study revealed that the drug showed changes driven primarily by a decrease in prevalence among patients diagnosed with post-traumatic stress disorder. For further information, please check the detailed study.

A clinical trial with Mifepristone:

The first clinical trial for Mifepristone started in 2012. A high dose of this medicine activates the glucocorticoid receptors in the central nervous system. It helps the patient to reduce the stress & anxiety caused due to their traumatic past.

The major outcomes associated with this trial included a Change in scores of CAPS intrusive symptoms and a change in scores of CAPS Avoidance symptoms. In addition, there was a change in scores of CAPS Hyperarousal symptoms.

Next, a change in depression & sleep quality, a change in severity associated with PTSD & Change in plasma cortisol.

Case of Psychopharmacologic Treatments for patients diagnosed with PTSD:

PTSD patients take four kinds of medicines. There are two types of antidepressants: SSRIs and SNRIs. The term SSRI refers to Selective Serotonin Reuptake Inhibitors & the term SNRI refers to Serotonin Norepinephrine Reuptake Inhibitors.

The medicines that fall under this category are Sertraline, Fluoxetine, Paroxetine, & Venlafaxine. By giving these medicines to the patients, their brains are able to cope with stress and relax.

Currently, there are no brand-new medicines effective in treating this disorder. So, in that case, the patients take these medicines as mentioned above & see if their anxiety, stress, behavior, & other symptoms changed.

In addition, we can categorize pharmacotherapy into different sections that include:

Antidepressants with slow action:

According to the American Psychiatric Association, SSRIs are effective in a few clinical trials conducted to examine changes in PTSD patients. As only sertraline and paroxetine are FDA-approved, you can count these medicines as legally prescribed for this disorder.

Antipsychotics for PTSD:

In general cases, patients with post-traumatic stress disorder take antipsychotic drugs like quetiapine, risperidone, and olanzapine. It is because these medicines show positive results in patients with early-onset of hyperarousal symptoms. Even the Beta-blockers reduce anxiety issues and control high blood pressure caused by anxiety.

Facts related to the common cases of PTSD:

If we consider the entire population of the United States of America,

  • Out of every 100 people, 6 suffer with post-traumatic stress disorder at some point during their lives.
  • Approximately twelve million people take antipsychotic drugs on a yearly basis because they want treat their disorders.
  • After comparing women with men, experts have revealed that women are more prone to this problem than men. This is because the majority of these cases relate to domestic abuse.

Case History of Post-Traumatic Relationship Syndrome:

PTRS disorder is the diagnosis for people who are heartbroken in a relationship. Those who cannot confess their feelings to a loved one also suffer from the same problem.

This causes a lot of stress for such people & may even lead to some traumatic events. These events include emotional, physical, sexual, and psychological abuse.

The following treatment plans are available to such people:

CPT – Cognitive Processing Therapy:

There are twelve-week-long therapy sessions for the patients, and each session includes a conversation between the patient and the in-charge person to change beliefs related to their traumatic past.

TF-CBT – Trauma Focused

When it comes to small children and adolescents, trauma-focused cognitive processing therapy is the typical solution. It takes approximately twenty-five to eight sessions to alleviate the trauma symptoms and determine the underlying causes of the disorder.

Prolonged Exposure:

Commonly known as PE, this treatment plan extends for three months and each session continues for sixty to one hundred twenty minutes. The patients experience a scenario that is similar to the trauma they have experienced and track the trigger point.


So, if we want to know how a person can bring himself or herself back from this painful & debilitating situation, first, we need to understand the root cause. After that, we can consult a good psychotherapist or psychiatrist who can diagnose the problem accurately.

Based on that diagnosis a treatment plan will be developed, as well as the outcome will be tracked. There are case histories and clinical trials that tell us everything about the medications prescribed to such patients.

By checking all the details, we get a clearer picture of how to handle patients who suffer from this illness.

Additionally, patients with PTRS should take counseling sessions because sometimes people fail to express their feelings or understand the behavior of others, which makes them overly aggressive.

Be on the safer side, take care of your mental health, and believe that everything has a solution. All you need to do is to talk to whomever you wish to.